Decreased
sex hormone binding globulin predicts noninsulin dependent diabetes mellitus in women but not in men.
According to the company, the
Sex Hormone Binding Globulin is an important biomarker used in the diagnosis and treatment of men's health.
Test principle for
sex hormone binding globulin and testosterone
3 13 B51/B55 Ankylosing spondylitis 1 13.3 B27 2 12.2 B27 3 11.5 B51/B57 4 11.0 B51/B27 5 10.1 B27 17-OH-P: 17-OH-progesterone; ACTH: adrenocorticotropic hormone; T: testosterone; SHBG:
sex hormone binding globulin; DHEAS: dehydroepiandrosterone sulfate; HLA: human leukocyte antigen Table 2.
Sex hormone binding globulin (SHBG) is primarily synthesized in the liver, binds androgens, and estrogen with high affinity, thereby lowering circulating steroid hormones and rendering them biologically unavailable to target tissues [123].
Gapstur et al., "Sex hormones,
sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA)," Atherosclerosis, vol.
Fasting blood samples of the participants were analyzed for serum
sex hormone binding globulin (SHBG), fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c) and fasting insulin levels.
Associations of serum
sex hormone binding globulin (SHBG) levels with SHBG gene polymorphisms in the CARDIA Male Hormone Study.
Adiposity, chronic inflammation, and the prepubertal decline of
sex hormone binding globulin in children: evidence for associations with the timing of puberty (Earlybird 58).
Sex hormone binding globulin and risk factors for breast cancer in a population of normal women who had never used exogenous sex hormones.
Because oral estrogens increase
sex hormone binding globulin, oral contraceptives could help ameliorate symptoms commonly associated with the diagnosis of PCOS--specifically, androgenic presentations.
The hyperinsulinemic state inherent in MS leads to inhibition of the hepatic production of
sex hormone binding globulin (SHBG), with a consequent decrease in the total testosterone levels.