Results: For all patients, no significant difference was found in mRNA expressions of human
telomerase reverse transcriptase and dyskerin (p>0.05), although their levels in tumour tissues were found to be higher than in normal tissues.
We next determined the STAT3 binding to hTERT (human
telomerase reverse transcriptase) promoter region.
Leptin upregulates telomerase activity and transcription of human
telomerase reverse transcriptase in MCF-7 breast cancer cells.
Human
telomerase reverse transcriptase and survivin immunoreactivity were exclusively observed in nuclear patterns.
The authors measured LTL, as well as mRNA expression and promoter DNA methylation of the telomerase catalytic enzyme gene [human
telomerase reverse transcriptase (hTERT), in blood samples obtained on the first day of a workweek and after 3 days of work and found that short-term exposure to PM was associated with a rapid increase in blood LTL.
The topics include generating cytotoxic T lymphocytes for the immunotherapy of EBV-associated malignancies, the enhanced migration of human dendritic cells expressing inducible CD40, constructing human antibody gene libraries and selecting antibodies by phage display, using
telomerase reverse transcriptase to identify immunogenic peptides of the self-tumor antigen, liposomes for gene transfer in cancer therapy, and the cellular immunotherapy of cancer.
baicalensis led to the inhibition of human
telomerase reverse transcriptase (hTERT), human telomerase-associated protein 1 (hTP1) and c-myc messenger ribonucleic acid (m-RNA) expression.
ABBREVIATIONS: hTERT = human
telomerase reverse transcriptase; hTR or hTERC = human telomerase RNA component; PCR = polymerase chain reaction; RUO = research use only; TRAP = telomeric repeat amplification protocol.
This virus has been modified so that it will specifically replicate in the majority of tumors which express an enzyme called human
telomerase reverse transcriptase, that is not found in most normal tissues.
In a retrospective multicenter study of 201 patients, positive staining for human
telomerase reverse transcriptase (hTERT) in the nucleolus was associated with a twofold higher relative risk of dying after curative resection for hepatic colorectal metastases; the increase was statistically significant (J.