| Acronym | Definition |
|---|
| TCO | Total Cost of Ownership |
| TCO | Take Care Of |
| TCO | Tjänstemännens Centralorganisation (Swedish Confederation of Professional Employees) |
| TCO | Taken Care Of |
| TCO | The Cinematic Orchestra (band) |
| TCO | Transnational Criminal Organization |
| TCO | Trust Company (band) |
| TCO | Transparent Conductive Oxide |
| TCO | True Cost to Own |
| TCO | Technology Commercialization Office |
| TCO | Tobacco Control Office (various locations) |
| TCO | The Chosen One |
| TCO | Tiffany & Co (jewelry company) |
| TCO | Temporary Certificate of Occupancy |
| TCO | Tierras Comunitarias de Origen (Original Communal Lands) |
| TCO | Taipei Chinese Orchestra (Taiwan) |
| TCO | Trust Company of the Ozarks (Springfield, MO) |
| TCO | The Corporate Office |
| TCO | Total Cost of Operations |
| TCO | True Cost of Ownership |
| TCO | Tail Call Optimization (computer programming) |
| TCO | Thermal Cut-Off (thermal fuse) |
| TCO | Termination Contracting Officer |
| TCO | Tax Credit Office (UK) |
| TCO | Tjänstemännens Central Organisation |
| TCO | Total Cost of Outsourcing |
| TCO | Total Column Ozone |
| TCO | Terrestrial Carbon Observations |
| TCO | Tactical Combat Operations |
| TCO | Technical Cooperation Programme (meteorology) |
| TCO | Technology Cooperation Office |
| TCO | Tactical Control Officer |
| TCO | Twin Cities Originals (restaurants) |
| TCO | Test Content Outline |
| TCO | Tom Cunningham Orchestra |
| TCO | Temperature Controlled Oscillator |
| TCO | Totally Cool Operation |
| TCO | The Charmed Ones (TV show) |
| TCO | Temperature Compensated Oscillator |
| TCO | Terry's Chocolate Orange |
| TCO | Telecommunications Coordination Officer |
| TCO | Tempest Control Officer |
| TCO | Tallis Chamber Orchestra (Suffolk, UK) |
| TCO | Technical Contracting Office |
| TCO | Telecommunications Certification Officer |
| TCO | Trial Court Opinion |
| TCO | Transport Control Officer |
| TCO | Total Call Ownership |
| TCO | Technology Coordinating Paper |
| TCO | Tasmanian Community Online |
| TCO | Telecommunications Control Office |
| TCO | Telecommunications Certifying Office |
| TCO | Tyneside Chamber Orchestra (UK) |
| TCO | Trellis-Converging Offset |
| TCO | Thrust Cutoff |
| TCO | Tierras Comunales de Origen (Spanish: Communal Lands of Origin; indigenous territories; Bolivia) |
| TCO | Three Colleges Observatory (UNC Greensboro) |
| TCO | Treaty Compliance Office |
| TCO | Traction Control Override |
| TCO | Test Control Office/r |
| TCO | Telephone Control Office/r |
| TCO | Trade Change Order |
| TCO | Toxic Chemical Operations |
| TCO | Thorsman Company Oslo |
| TCO | Tennis Club de l'Oust (Saint-Vincent-sur-Oust, France) |