Long noncoding RNA
XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer.
Increased expression of long non-coding RNA
XIST predicts favorable prognosis of cervical squamous cell carcinoma subsequent to definitive chemoradiation therapy.
Xue et al., "Knockdown of long non-coding RNA
XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152," Cancer Letters, vol.
Researchers found that the gene
XIST, which is responsible for inactivating one of the two copies of the X chromosome in cells that store genetic material, works overtime in female patients with mental illnesses such as bipolar disorder, major depression, and schizophrenia.
Enox, a novel gene that maps 10 kb upstream of
Xist and partially escapes X inactivation.
The artistry on display in History Witch drew the attention of
Xist Publishing who collaborated with Lisa to develop Women in History, a series of elementary school books for girls focused on women's contributions throughout history.
lncRNAs play a critical role in the regulation of imprinting, exemplified by the long intergenic RNA Air, and X-chromosome inactivation by X-inactive specific transcript (
Xist) (8, 17).
Engreitz et al., "The
Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread across the X Chromosome," Science 341 (2013): 6147.