The affected Drospirenone and Ethinyl
Estradiol Tablets were identified as Lot number 183222, with NDC number 59746-763-43 and expiration date of 11/2020.
Ethinyl
estradiol is a synthetic estrogen that is widely used to treat menopausal symptoms and menstrual disorders and can be used in combination with progestin for contraception.
In 2016, the primary findings of the Early versus Late Intervention Trial with
Estradiol (ELITE) demonstrated that oral E2 administered to women who were less than 6 years postmenopause slowed progression of subclinical atherosclerosis as assessed by carotid artery intima-media thickness (CIMT), while it had no effect in women who were at least 10 years postmenopause.
The postmenopausal women included in this analysis all had baseline measurements of testosterone,
estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels between 2000 and 2002, according to the report.
Hormone detection (ELISA) of
estradiol and testosterone
The researchers observed a significantly greater improvement in total MENQOL scores for treatment with vaginal
estradiol compared with dual placebo (mean difference between arms, −0.3 at 12 weeks).
Regarding
estradiol's impact on exercise-induced muscle damage, one possible mechanism is its association with the myogenic activation of satellite cells to assist with muscle repair and regeneration during recovery (Farup et al., 2014).
Female reproductive efficiency--ovarian follicular development ovulation and embryo survival are controlled by steroid hormones progestagens (mainly progesterone) and estrogens (mainly
estradiol) (Fortune et al.
The present study examined the protective effects of treatment with
estradiol before resuscitation on myocardial contractile function following HS in a rat model.
Estradiol is a form of estrogen, and is a female sex hormone produced by the ovaries.