In a letter sent to Khaleej Times , Kaplan said: "The award, which is intended to recognise dedication to alleviating human suffering through research and standard services, comes with a substantial monetary prize that I would like to donate to the International
Fibrodysplasia Ossificans Progressiva Association (IFOPA) as a gift in memory of my beloved parents, Harold and Elaine Kaplan."
Horigome et al., "Neofunction of ACVR1 in
fibrodysplasia ossificans progressiva," Proceedings of the National Academy of Sciences of the United States of America, vol.
Kaplan, "Acute lymphocytic infiltration in an extremely early lesion of
fibrodysplasia ossificans progressiva," Clinical Orthopaedics and Related Research, vol.
Three types of
Fibrodysplasia Ossificans Progressiva have been described; Typical, Atypical and Variant types (Table 1).
Jasmine has
fibrodysplasia ossificans progressiva, FOP, which means that when her muscles, ligaments and tissue are damaged, they turn into bone.
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic
fibrodysplasia ossificans progressiva. Nat Genet 2006 May; 38(5):525-527.
Citation: "Induced pluripotent stem cells from patients with human
fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation"; Yoshihisa Matsumoto et al.; Orphanet Journal of Rare Diseases, 2013; 8(1): 190 DOI: 10.1186/1750-1172-8-190
FOP (
fibrodysplasia ossificans progressiva) is some-times called stone man syndrome and is a genetic mutation of the body's repair mechanism.
Having read the very interesting case history of the four-year-old boy with
fibrodysplasia ossificans progressiva requiring an emergency tracheostomy for a 'can't intubate, can't oxygenate' recently published by Santoro et al (1), I was reminded of the difficult airway teaching I received as a registrar.
Fraserburgh, Aberdeenshire Fashion fanatic Louise suffers from rare genetic condition
fibrodysplasia ossificans progressiva, which causes soft tissue to turn into bone.
However, Louise faces an extra challenge as she tries to break into this competitive and often cut-throat industry - she suffers from
Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic condition which causes her joints to lock as her muscles start to turn to bone.
The Human Mannequin (C4, 9pm) Scottish teen Louise Wedderbun hoping to turn her passion for fashion into a career - though she suffers from
Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic condition that causes her joins to lock as her muscles start to turn to bone.