Homeobox genes are characterized by a conserved 180-bp DNA sequence coding for a 60-aminoacid DNA-binding domain called the 'homeodomain.
Roles of the middle domain-specific WUSCHEL-RELATED
HOMEOBOX genes in early development of leaves in Arabidopsis.
Homeobox genleri " master genler" olarak da bilinirler.
(20.) Harvey RR NK-2
homeobox genes and heart development.
Some of the genetic disorders associated with infantile spasms are X-linked cyclin-dependent kinase-like 5 (CDKL5 or Stk9) disruption, (6) deletion of the membrane associated guanylate kinase, WW and PDZ domain containing 2 (MAGI2) gene, (7) disruption of the serine/threonine kinase 9 gene, (8) distal 7q duplication syndrome, (9) expansion of the first PolyA tract of aristaless-related
homeobox gene (ARX), (10) filamin A (FLNA) mutations, (11) and interstitial deletion of 7q.
Immunohistochemical staining of tumour tissue was negative for prostate-specific antigen (PSA) and prostate-specific acid phosphatase, strongly positive for cytokeratin (CK) 7/20/ carcinoembryonic antigen (CEA), strong nuclear positive for caudal-related
homeobox 2 (CDX2) and negative staining for CK5/6.
Advances in the field of genetics have estimated that about 2% of idiopathic short stature is related to haplo-insufficiency of the short stature
homeobox (SHOX) gene, which is found on the short arm of the X and Y chromosomes in the pseudo-autosomal region.
Members of the Antennapedia class of
homeobox genes, known as Hox genes, are believed to be pivotal in regulating vertebrate craniofacial development and controlling morphogenesis and the growth of the proximal-distal axis.
Otx2
homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue.
One of these patterns called
homeobox is found in all cells except bacteria which are not complex enough for this differentiation.