According to the company, Unituxin is a GD2-binding monoclonal antibody indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF),
interleukin-2 (IL-2), and 13-cis-retinoic acid (RA) for high-risk neuroblastoma.
Increased serum autoantibodies against human
interleukin-2 in systemic lupus erythematosus patients
* The report provides a snapshot of the global therapeutic landscape for
Interleukin-2 Receptor Subunit Alpha (IL-2 Receptor Subunit Alpha or TAC Antigen or p55 or CD25)
Interleukin-2 can be highly effective when delivered before immune-suppressing conventional therapies.
Change in Serum Concentrations of
Interleukin-2 and Interferon-[gamma] During Treatment of Tuberculosis.
About 16 percent of study participants given the vaccine and
Interleukin-2 combination saw tumors shrink by 50 percent or more, compared to 6 percent given
Interleukin-2 alone.
Interleukin-2 (IL-2), described as T-cell growth factor (Morgan et al., 1976), is a polypeptide of an apparent relative molecular weight of 15,500.
Controlled trial of
interleukin-2 infusions in patients infected with the human immunodeficiency virus.
Maternal serum interleukin 1, 2, 6, 8 and
interleukin-2 receptor levels in preterm labor and delivery.
Interleukin-2 receptor antibodies block the release of a hormone activated as an immune response to a foreign body, like a new kidney.
Furthermore, a Major Histocompatibility Complex (MHC)-class-I-restricted T cell activation ELISPOT assay showed elevated interferon- [gamma],
interleukin-2, and interleukin-12 production in HA/SHIV 89.6 VLP-immunized mice, indicating that phenotypically mixed HA/SHIV 89.6 VLPs can enhance both humoral and cellular immune responses at multiple mucosal sites.
The detection of this immuno-depression is possible through the measurement of the levels of secreted
interleukin-2 (IL2) and interleukin-4 (IL4) found in peripheral blood mononuclear cells (PBMC).