| Acronym | Definition |
|---|
| ISS | International Space Station |
| ISS | Issue |
| ISS | Information Systems Services |
| ISS | Infamous: Second Son (gaming) |
| ISS | Institute for Security Studies |
| ISS | Internet Security Systems, Inc. |
| ISS | Initial (Execution) Sequence Set |
| ISS | Institute for Southern Studies |
| ISS | Islands |
| ISS | Information Systems Security |
| ISS | Istituto Superiore di Sanità (Italian National Institute of Health) |
| ISS | Imaging Science Subsystem (NASA Cassini mission) |
| ISS | Instruction and Student Services (various schools) |
| ISS | Institutional Shareholder Services |
| ISS | Instructional Support Services (various locations) |
| ISS | Idea Star Singer (TV reality show; India) |
| ISS | Installation Support Services |
| ISS | Injury Severity Score |
| ISS | Inferred from Sequence Similarity (gene ontology) |
| ISS | Iredell-Statesville Schools (Statesville, NC) |
| ISS | In-School Suspension |
| ISS | Instruction Set Simulator |
| ISS | Indian Springs School (Shelby, AL) |
| ISS | International Superstar Soccer (gaming) |
| ISS | International Students and Scholars (various schools) |
| ISS | Illinois State Society |
| ISS | Input-to-State Stability (mathematics) |
| ISS | International Summer School (various locations) |
| ISS | Industry Security Services (defense industry, UK) |
| ISS | Innovative Service Solutions (Florida) |
| ISS | International Scientific Symposium (various meanings) |
| ISS | Imposto Sobre Serviços (Brazilian tax) |
| ISS | Internal Seminar Series (various organizations) |
| ISS | Institute of Systems Science (National University of Singapore) |
| ISS | International Staging System (myeloma) |
| ISS | Ionic Silver Stick (antimcrobial device) |
| ISS | International Social Service (Switzerland) |
| ISS | Instituto Sedes Sapientiae (Portuguese; Seat of Wisdom Institute; Brazil) |
| ISS | Iron and Steel Society |
| ISS | Investigative Security Services (various companies) |
| ISS | Institutt for Sosiologi og Samfunnsgeografi (Norwegian: Department of Sociology and Human Geography) |
| ISS | Interaction Sol Structure (French: Soil Structure Interaction) |
| ISS | Insight Software Solutions, Inc. |
| ISS | Istanbul Street Style (Istanbul, Turkey) |
| ISS | International Software Solutions (various locations) |
| ISS | Integrated Summary of Safety (US FDA) |
| ISS | Information Services and Systems |
| ISS | International Student Survey |
| ISS | Intelligent Security Systems (video technology) |
| ISS | Irish and Scottish Studies (UK) |
| ISS | International Seapower Symposium (est. 1969) |
| ISS | Instituto de Seguros Sociales (Colombia) |
| ISS | International Security Solutions (Washington, DC) |
| ISS | Integrated Storage Solution |
| ISS | Inactive Shadow Set |
| ISS | Image Symbol Set |
| ISS | Intelligent Storage System |
| ISS | Intel Solutions Summit |
| ISS | Income Support Supplement |
| ISS | Image Sensor Solutions |
| ISS | Index Search System |
| ISS | Internet Security Systems |
| ISS | Inno Setup Script |
| ISS | Intel Speed Step |
| ISS | Inhibit Symmetric Swapping |
| ISS | Initial Send Sequence |
| ISS | Industry Standard Servers |
| ISS | International Schools Services (est. 1955; Princeton, NJ) |
| ISS | Injoy Stewardship Services (church capital campaigns; New York) |
| ISS | Institute of Sustainability Science (Kyoto University; Japan) |
| ISS | Industry-Supported Symposia |
| ISS | Internet Security Scanner |
| ISS | In-Store Special (retail) |
| ISS | Infoseek Software Systems (India) |
| ISS | Institute of Social Sciences |
| ISS | Information Security Services |
| ISS | International Science School (various locations) |
| ISS | In-Service Support |
| ISS | Inno Setup Script (Windows installer program) |
| ISS | Ion Scattering Spectroscopy |
| ISS | International Shakuhachi Society (Japanese bamboo flute) |
| ISS | International Skeletal Society |
| ISS | International Satellite Services (Florida) |
| ISS | Integrated Systems Solutions |
| ISS | International Society of Surgery |
| ISS | Integrated Service Solutions |
| ISS | Integrated Solutions & Services, Inc. (various locations) |
| ISS | Information Software Systems (various locations) |
| ISS | Inspection Selection System (roadside inspection software system) |
| ISS | Infoxchange Service Seeker (health directory; Australia) |
| ISS | Inside Surface |
| ISS | Integral Shaft Support |
| ISS | International Switching Symposium |
| ISS | Internet Success System (business training) |
| ISS | Imprinted Sportswear Shows |
| ISS | I'm So Sure |
| ISS | Institute of Space Science |
| ISS | Integrated Sounding System |
| ISS | International Shorebird Survey (Manomet Observatory, Manomet, MA) |
| ISS | Information Systems Support, Inc |
| ISS | Integrated Safety System |
| ISS | Integrated Survey System |
| ISS | Internal Security Service (Oman) |
| ISS | Integrated Sensor System |
| ISS | Intelligence Support System |
| ISS | Information Systems Staff |
| ISS | Input Shaft Speed |
| ISS | Integrated Server and Storage (various companies) |
| ISS | Inter-Satellite Service |
| ISS | Instructional Systems Specialist |
| ISS | Ion Scattering Spectrometry |
| ISS | Immigrant Services Society of British Columbia (Canada) |
| ISS | Intel Solution Services |
| ISS | Integrated Support System |
| ISS | Instant Start System |
| ISS | International School of Singapore |
| ISS | Integrated Space Systems |
| ISS | Interactive Selling System |
| ISS | Integrated Support Service |
| ISS | Image Stabilization System |
| ISS | International Seismological Summary |
| ISS | Impedance Standard Substrate |
| ISS | International School Sosua (Dominican Republic) |
| ISS | Internet Sharing Server |
| ISS | Intelligent Software Solutions, Inc (Raleigh, North Carolina) |
| ISS | Intelligent Sensor Systems (Malardalen University; Sweden) |
| ISS | Instrument Support Structure |
| ISS | Information Sending Signal |
| ISS | Integrated Switching System |
| ISS | Interim Supply Support |
| ISS | International Survivalist Society |
| ISS | Internet Search Service(s) |
| ISS | Isotonic Saline Solution |
| ISS | Institute of Statistical Science |
| ISS | Iris Spinning Stage (US NASA) |
| ISS | In Stadium Solutions (Coral Springs, FL) |
| ISS | Immunization Services Support (WHO) |
| ISS | IranskSvenska Solidaritetsföreningen |
| ISS | Instructional Support System |
| ISS | Intelligence Support Squadron |
| ISS | Instrument Sales and Service, Inc. |
| ISS | Interim Status Standards |
| ISS | Indian Staging Section |
| ISS | Intelligence Systems Secretariat |
| ISS | Isuzu Systems Service (Japan) |
| ISS | Imperial Star Ship (Star Trek) |
| ISS | Intermediate Service School |
| ISS | Institute of Software Systems (various locations) |
| ISS | Isotope Separation System |
| ISS | Information and Systems Society |
| ISS | International Shaw Society (est. 2002) |
| ISS | Information Sharing Session |
| ISS | Insulin Sliding Scale |
| ISS | International Soccer Superstar (video game) |
| ISS | Improved Spread Spectrum (watermarking) |
| ISS | International School Seychelles (Mahé, Seychelles) |
| ISS | Image Server System |
| ISS | Input Sub System |
| ISS | Internal Secondary Structure |
| ISS | Integrated Support Station |
| ISS | Information Systems Squadron |
| ISS | International Sales Support |
| ISS | Inertial Survey System |
| ISS | Institute for State Studies |
| ISS | International Sanitary Systems |
| ISS | Interactive Support System |
| ISS | Interservice Supply Support |
| ISS | Image Synthesis Services |
| ISS | Integrated System Support |
| ISS | Information Superiority and Sensors |
| ISS | Interactive Survivability Simulation |
| ISS | Integrated SS7 Signaling |
| ISS | Infrared Surveillance Sensor |
| ISS | Intelligent Server Switch (Apache) |
| ISS | International Supply Services (Portsmouth, VA) |
| ISS | International Scoring Systems (Paris, France) |
| ISS | Interim Safety Supplement |
| ISS | InfraStructure Systems GmbH (Hanover, Germany) |
| ISS | Integrated Sealift Study |
| ISS | Inventory Support Specialist |
| ISS | Independent School Services |
| ISS | Incoming Signal Strength |
| ISS | Integrated Start System |
| ISS | Institute of Somatic Sciences |
| ISS | IAIPS Support Services |
| ISS | Infinite Server Station |
| ISS | Ingleside State School (Gold Coast, Australia) |
| ISS | Investment Statistical System |
| ISS | Information Sending Service |
| ISS | Infusion Signaling Server |
| ISS | International Settlement System |
| ISS | Integrated System Schedule |
| ISS | Indirect/Inertial Subsystem |
| ISS | Internal Secondary Storage |
| ISS | Initial Shelf Stock |