| Acronym | Definition |
|---|
| NIC | National Institute of Corrections (Federal Agency) |
| NIC | National Informatics Centre (Department of Information Technology, government of India) |
| NIC | Network Interface Card |
| NIC | Network Information Center |
| NIC | National Insurance Contributions (UK tax) |
| NIC | Nicola |
| NIC | National Intelligence Council |
| NIC | Nicaragua (ISO Country code) |
| NIC | Network Interface Controller |
| NIC | Not In Contact (Sprint) |
| NIC | Not in Contract (construction) |
| NIC | Nicotine |
| NIC | Nursing Interventions Classification |
| NIC | National Instruments Corporation (India) |
| NIC | Nurse in Charge |
| NIC | North Idaho College (Coeur d'Alene, Idaho) |
| NIC | North Island College (British Columbia, Canada) |
| NIC | New In Chess |
| NIC | Normas Internacionales de Contabilidad (Spanish) |
| NIC | National Information Center |
| NIC | John von Neumann Institute for Computing |
| NIC | Nuclei in the Cosmos (symposium) |
| NIC | National Insurance Company (India) |
| NIC | Neumann Institute for Computing (Germany) |
| NIC | National Innovation Council (India) |
| NIC | Network Integration Center |
| NIC | New Imaging Concept |
| NIC | Nagoya International Center (Japan) |
| NIC | National Identity Card (Pakistan) |
| NIC | National Ice Center (US) |
| NIC | National Incident Commander (US DHS) |
| NIC | New Internet Computer (Oracle) |
| NIC | Nazionale Italiana Cantanti (Italian: National Italian Singers) |
| NIC | Newly Industrialized Country |
| NIC | Notice of Intended Changes |
| NIC | Naval Intelligence Center (US DoD) |
| NIC | Navigation Integrity Category (avionics) |
| NIC | Net Interest Cost |
| NIC | Newly Industrializing Country (NIE) |
| NIC | Noise Isolation Class (sound transmission loss rating) |
| NIC | Nissho Iwai Corporation (Japan) |
| NIC | National Innovation Competition (various locations) |
| NIC | National Issues Convention |
| NIC | Network Identification Code (ITU-T) |
| NIC | National Industrial Classification (India) |
| NIC | Near Infrared Camera |
| NIC | Numeric Intensive Computing |
| NIC | Natal Indian Congress (South Africa) |
| NIC | National Intelligence Community |
| NIC | Nihongo Instructor Club (Japan) |
| NIC | National Investment Center for the Seniors Housing & Care Industry (Annapolis, MD) |
| NIC | National Irrigation Commission |
| NIC | Nerf Internet Community |
| NIC | Network Information Computer (Digital Lightwave) |
| NIC | Negative Impedance Converter |
| NIC | Network Interface Connector |
| NIC | Naval Intelligence Command |
| NIC | National ISDN Council |
| NIC | Nikon Integrated Coating |
| NIC | National Interpreting Certification (American Sign Language) |
| NIC | Network Interface Circuit |
| NIC | National-Interstate Council of State Boards of Cosmetology, Inc. |
| NIC | Network Integration Center (US NASA) |
| NIC | North American Inter-fraternity Conference |
| NIC | Nephron Information Center |
| NIC | National Instrumentation Center |
| NIC | National Immigration Conference (National Industrial Conference Board) |
| NIC | Nauru Island Council |
| NIC | Not in Catalog (retail) |
| NIC | Not Included in Cost |
| NIC | New Industrialized Country |
| NIC | Night Infiltration Course |
| NIC | Near Instantaneous Companding |
| NIC | National Inventors Council |
| NIC | National Isotope Centre (New Zealand) |
| NIC | National Intelligence Cells |
| NIC | Network Invasion Charlotte |
| NIC | Nevada Industrial Commission |
| NIC | NATO International Civilian |
| NIC | National Identification Code |
| NIC | Notice of Intent to Conclude |
| NIC | Naval Information Center |
| NIC | Network Interface Codes |
| NIC | Normas Internacinales de Contabilidad |
| NIC | Network Initiated Change |
| NIC | Newcomers Information Centre (Toronto, Canada) |
| NIC | NIMS (National Incident Management System) Integration Center (US DHS/FEMA) |
| NIC | Nicosia, Cyprus - International Airport (Airport Code, closed since 1974 until further notice) |
| NIC | Navigation Integrity Code (US FAA) |