In a study by Xia et al they found defect types of retinal nerve fiber layer: RNFL diffuse loss and local defect ratio were 53.19% and 4.26% in Primary open angle glaucoma, respectively, while were 21.05% and 55.26% in
Normal tension glaucoma respectively30.
Gandolfo, "Effect of Ginkgo biloba extract on preexisting visual field damage in
normal tension glaucoma," Ophthalmology, vol.
Analysis of myocilin mutations in Japanese patients with
normal tension glaucoma and primary open angle glaucoma.
People with
normal tension glaucoma tend to have thinner corneas than average, which may mean that we are underestimating their true intraocular pressures.
Limitations of the study: In our study, ample size was small, measurement of RNFL-T was done by relatively old machine, and patients with ocular hypertension,
normal tension glaucoma and PACG were not included.
Normal Tension Glaucoma Study (NTGS) established that aggressive IOP reduction (30%) reduced VF worsening from 30% to 10% over 5 yrs.(5) In the Advanced Glaucoma Intervention Study (AGIS), there was a clear IOP 'dose response' relationship with visual field progression, which showed a striking lack of visual field progression in patients who had a mean IOP of 12.3 mmHg.
[55] proved that the changes in ocular perfusion pressure induced by the circadian fluctuation of blood pressure might account for the progression index in
normal tension glaucoma.
A retrospective analysis was conducted on 332 Korean patients (mean age, 52.9 years) with
normal tension glaucoma who were treated with 60 mg of anthocyanins (n = 132) or 80 mg of Ginkgo biloba extract (ginkgo; n = 103) twice a day or no medication (controls; n = 97) for a mean duration of 2 years (range, 6-59 months).
Many individuals can harbor significant optic nerve damage, yet maintain eye pressures within the accepted guidelines, a condition called
normal tension glaucoma (NTG).
Enhanced depth imaging detects lamina cribrosa thickness differences in
normal tension glaucoma and primary open-angle glaucoma.
Hitchings, "Motion detection threshold and field progression in
normal tension glaucoma," The British Journal of Ophthalmology, vol.