Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either
oligodendroglioma or astrocytoma.
Oligodendrogliomas are tumours that originate in the brain instead of spreading from elsewhere.
The presence of fibrillary material, fine capillary network, and clinging of cells around vessels led to the erroneous diagnosis of
oligodendroglioma. Panel b: H and E stained section of the same tumor revealed features of a low-grade astrocytoma
Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic
oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402.
In this classification scheme,
oligodendrogliomas are divided into two forms: the well-differentiated
oligodendroglioma and the less common anaplastic
oligodendroglioma.
Charlotte, aged 36, from Clayton West, has undergone three operations and had part of her skull removed in her three-year battle with a grade two
oligodendroglioma brain tumour
FISH for 1p19q codel, if histology suggests the possibility of an
oligodendroglioma or if mutant IDH is detected.
2011: Tumor treating fields is FDA approved for recurrent GBM 2013: 1p 19q co deletion is linked to favorable prognosis in patients with
oligodendroglioma 2015: Maintenance therapy of Tumor treating fields with temozolomide offers patients with GBM increased overall survival 2013-Present 2016: Advancements in immunotherapy for brain tumor patients that include cellular therapies and vaccine therapies.
As a young man planning to start a family, my long-term health and quality of life were important considerations when selecting my treatment," said Paul Penke, who recently completed proton therapy to treat his Grade 3
Oligodendroglioma. "Despite the scientific literature showing how effective proton therapy is at treating cancers of the brain, my insurer denied payment.
While 6 (17.1%) patients from supratentorial group were diagnosed as
oligodendroglioma with low grade and anaplastic features in 4 (66.7%) and 2 (33.3%) respectively.
Andrew Brown, 27, was diagnosed with stage three anaplastic
oligodendroglioma in September last year after suffering several "violent" seizures.
After travelling to hospital in Cardiff with Meisha, his mother and sister to receive results from a biopsy, Andrew was diagnosed with stage three anaplastic
oligodendroglioma. Doctors said the tumour was inoperable, and have given Andrew between three and five years to live.