Platelet-derived growth factor receptor-[alpha]/CEP4 centromere ratio was assessed.
Westermark, "Mechanism of action and in vivo role of
platelet-derived growth factor," Physiological Reviews, vol.
EGF: epidermal growth factor; TGF-[alpha]: transforming growth factor; b-NGF: basic nerve growth factor; PDGF-bb:
platelet-derived growth factor; b-FGF: basic fibroblast growth factor; and IL: interleukin.
Imatinib mesylate (Glivec) is a tyrosine kinase inhibitor (TKI) that inhibits both the
platelet-derived growth factor receptor (PDGFR) and the C-kit receptor.
Platelet-derived growth factor. Distinct signal transduction pathways associated with migration versus proliferation.
Platelet-rich plasma (PRP), a plasma preparation with variable concentrations of platelets (PLTs) and white blood cells (WBCs), is a biomaterial rich in growth factors (GFs), such as transforming growth factor beta-1 (TGF-[[beta].sub.1]) and
platelet-derived growth factor type BB (PDGF-BB) [1].
They studied a protein called
platelet-derived growth factor receptor alpha, or PDGFR alpha, that sits on the surface of muscle-embedded stem cells called fibro-adipogenic progenitors, or FAPs.
Flow cytometry assay showed that MSCs expressed high levels of these growth factor receptors, such as
platelet-derived growth factor A and B and TGF-[beta]1 receptors (9).
They found a variety of factors that stimulated proliferation, including the proteins desert hedgehog (DHH), basic fibroblast growth factor,
platelet-derived growth factor and activin.
Growth factors like
platelet-derived growth factor (PDGF) and stem cell factor (SCF) are naturally occurring substances capable of stimulating cellular growth, proliferation and differentiation.
Association of
platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumours.
The highly expressed growth factor receptor genes, meanwhile, were
platelet-derived growth factor receptor-like protein,
platelet-derived growth factor receptor (beta polypeptide), autocrine motility factor receptor, transforming growth factor beta type 2 receptor, epidermal growth factor receptor, and insulin-like growth factor 2 receptor (IGF2R).