Acronyms

PI

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PIPrivate Investigator
PIPolitically Incorrect
PIPer Inquiry
PI[not an acronym] name for Greek symbol representing the ratio of the circumference of a circle to its diameter; approximately 3.1416
PIPisa (Tuscany, Italy)
PIPlug In
PIProduct Information
PIPrivate Investigations (movie)
PIProcess Integration
PIPhase I (clinical studies)
PIPrincipal Investigator
PIPublic Information
PIProgram Improvement
PIProcess Improvement
PIPersonal Injury (legal)
PIPhosphate (Inorganic)
PIProtease Inhibitor
PIProfessional Indemnity (insurance coverage)
PIPoison Ivy
PIPlant Industry (Commonwealth Scientific and Industrial Research Organisation; Australia)
PIPackage Insert (medications)
PIProgram Information
PIPerformance Improvement
PIPiauí (Brazilian state)
PIPost Intelligencer (newspaper, Seattle, Washington)
PIProcessing Instruction
PIPolyimide (polymer)
PIPunto Informatico
PIPer Inch
PIPoint of Intersection
PIPoint of Impact
PIPleasure Island (Disney World)
PIPolicy and International Affairs
PIPinellas (plant; Florida)
PIPrescribing Information (medication)
PIPhiladelphia Inquirer (newspaper)
PIPaging (assembly language ASM51 assembler control)
PIPerformance Index
PIPrivacy Information (UK)
PIPinneberg (auto license plate)
PIPetroleum Institute
PIPCNA (Proliferating Cell Nuclear Antigen) Labeling Index
PIPerformance Indicator
PIPublic Involvement (various locations)
PIParental Involvement (various organizations)
PIPolice Interceptor
PIPersonal Inspection
PIPrivacy International (human rights group)
PIProprietary Information
PIPulse Induction
PIPhysik Instrumente
PIPlasticity Index
PIPlease Inquire
PIProgram Instructions
PIPresque Isle (Michigan)
PIPropidium Iodide
PIPoint of Inflection (engineering)
PIPhysikalisches Institut (German: Institute of Physics)
PIProportional-Integral (controller)
PIPrimer Impacto (TV show)
PIIsoelectric Point (chemistry)
PIProcess Industries
PIPulmonary Infection (lungs)
PIPhysical Inventory
PIPlaque Index (oral hygiene)
PIPredictive Index
PIPersistently Infected
PIPeriodic Inspection
PIPlant Information (real-time software products such as SCADA)
PIPhotoImpact (digital imaging software)
PIPropriedade Intelectual (Intellectual Property, Brazil)
PIProject Impact (various organizations)
PIPremature Infant
PIPacific Institute
PIPenile Implant
PIBlood Clotting
PIPersonal Investigator (less common)
PIPerpetual Inventory
PIParris Island
PIPlanet Internet
PIPreliminary Injunction
PIPolynomial Identity (mathematics)
PIPhoto Interpretation
PIPolyisocyanurate (rigid foam contruction material)
PIPhysics International
PIPasses Intercepted (soccer)
PIPlatform Integration (various organizations)
PIPower Integrations
PIPerimeter Institute for Theoretical Physics
PIPass Interference (football)
PIPandemic Influenza
PIPolicy Issuance (insurance)
PIPrivate Idaho
PIProgram Introduction (various organizations)
PIPraktische Informatik (German: Applied Informatics)
PIPrimary Immunodeficiency
PIPaedagogisches Institut (Vienna, Austria)
PIProgram Integrity
PIProgram Increment
PIPhysically Impaired
PIProcess & Instrumentation
PIPeripheral Iridotomy
PIPonderal Index
PIPhilippine Islands (slang)
PIProject Inspector (various locations)
PIPerformance Insight (Oracle)
PIPersonal Identifier
PIPulmonary Insufficiency (cardiac measurement)
PIPentium I (Intel)
PIPaternity Index
PIParallel Interface
PIPlant Integrity
PIPosition Indicator
PIPublic Intoxication (law enforcement)
PIPurchase Intent (marketing)
PIPulsatility Index
PIProduct Integration
PIPower Interface
PIPearl Islands (Hawaii)
PIPhysician Information
PIProduct Improvement
PIProfitability Index
PIProgram Index
PIPopulation Institute
PIPlouffe's Inverter
PIPostinjection
PIPressure Indicator (industrial control description)
PIPacific Internet (Internet Service Provider)
PIPost Inoculation
PIPlatform Initialization (Specification)
PIPrecision Instrument
PIProductivity Index (oil and gas well performance)
PIParanormal Investigator
PIProvider Independent (IP address space assigned by IANA)
PIProgram Identification
PIProduction Insurance
PIPhoto Interpreter
PIProforma Invoice
PIProgrammed Instruction
PIProyectos Industriales
PIProject Identification (number)
PIProfitabilty Improvement
PIPrediction Interval
PIPacket Interface
PIPartner Institution
PIProductivity Increase
PIPage Impression (Internet advertising)
PIProduct Integrity
PIPriority Inheritance
PIProtocol Interpreter
PIPaper Insulated
PIInternational Protocol
PIPrison Industry
PIPerlite Institute (Staten Island, NY)
PIPoint Initiating
PIProgram Interruption
PIParanoid Ideation
PIPanicle Initiation
PIPhosphorus Index
PIPursuit Inc.
PIPaperi-Insinöörit (Finnish: Paper Engineers)
PIPar Intérim (French: Deputizing)
PIParameter Identifier (ITU-T)
PIIstiqlal Party (Independence Party, Morocco)
PIParticular Integral
PIPayload Integrator
PIPerforated Initials (philately)
PIPatente de Invenção (Patent, Brazil)
PIPhotographic Interpreter
PIPrime Implicant
PIPrimary Injection
PIProjets Individuels
PIPortable Interceptors
PIPopcorn Institute (Chicago, IL)
PIPigeon Trainer (US Navy)
PIPrimary Investigations
PIPurchasing Instruction
PIPusat Informasi (Indonesian: Information Center)
PIPrécompte Immobilier (French: tax on real estate)
PIParents for Inclusion
PIPrice Integrity
PIParadigm Infinitum (Singapore)
PIProgram Isolation (IBM)
PIPhysicist Interface
PIPraendex Incorporated (Wellesley, MA)
PIPrincipal Insured
PIPrintImage International
PIParameter Indicator
PIProspective Internationale
PIPerceptually Impaired
PIPulse Inverter
PIPerception Immédiate (French)
PIParent Initial
PIProjector Infantry
PIPsykoterapiinstitut (Stockholm, Sweden)
PIPaducah & Illinois Railroad
PIProcurement Instruction
PIPage Interleaving
PIProfessional Informant
PIPsicología Integrada (Portugese)
PIIonized Phosphorus
PIProto-I.jo
PIPassive Intercept
PIPampers Institute (UK)
PIProbationary Instructor
PIProfil Infirmier
PIPreliminary Investigation Coordinator (Canada)
PIPallidum Internum
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References in periodicals archive
PhRMA's Siegfried says that besides the protease inhibitors pharmaceutical firms are testing 10 immuno-modulator drugs designed to strengthen the body's immune system, 13 vaccines that could either treat or prevent HIV infection, over three dozen drugs that fight AIDS-related cancer and opportunistic infections, 41 antiviral medicines and four gene therapies.
On the other hand, HIV resistant to one protease inhibitor may not be resistant to all other protease inhibitors.
He adds that protease inhibitors like Norvir block the action of an enzyme involved in the final processing of the AIDS virus.
In this review, we would like to provide an overview of the application of click chemistry in the development of HIV protease inhibitors.
The decision to start or stop protease inhibitor therapy cannot be made on the basis of these findings on anal cancer and prostate cancer.
Antimicrobial activity studies on a trypsin-chymotrypsin protease inhibitor obtained from potato.
Protease inhibitors are substrates of cytochrome P450 isoenzyme 3A4 and P-glycoprotein (an efflux pump), both of which are induced by rifampicin.
Treatment using the Ghosh molecule has fewer associated side effects because the dose required is significantly less than those for existing protease inhibitors. The molecule also is smaller than those that make up current protease inhibitors and is much more easily absorbed and tolerated by the body.
With the accumulation of post-marketing data concerning concomitant administration of INVIRASE(R) and other drugs, it was found that concomitant use with HIV protease inhibitor ritonavir (product name: NORVIR(R))caused significant increase of blood INVIRASE(R) concentration.
In the first agreement, Medivir has outlicensed its preclinical human immunodeficiency virus (HIV) protease inhibitor project and in the second agreement provided a license for the MIV-210 polymerase inhibitor compound for HIV and hepatitis B (HBV).
Prezista (also called darunavir, or TMC-114), a new protease inhibitor active against many of the viruses resistant to other protease inhibitors, was approved by the FDA on June 23 "for the treatment of human immunodeficiency virus (HIV) infection in antiretroviral treatment-experienced adult patients, such as those with HIV-1 strains resistant to more than one protease inhibitor." In hard-to-treat patients already highly resistant to other antiretrovirals, 70% of patients taking Prezista together with other HIV treatments had a virologic response at week 24, vs.
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