(2018), Structure-Based Virtual Screening of LsrK Kinase Inhibitors to Target
Quorum Sensing. ChemMedChem.
Hence, considering the fact that interaction of Morin at binding site could quench the
quorum sensing ability and therefore disturb the cell wall synthesis and destruct the growth of the organism (unaccompanied data), if proven through wet lab studies, it may be applied for all 211 strains of Staphylococcus and other pathogens possessing LytTR domain in agrA proteins.
Quorum sensing and expression of virulence in Escherichia coli O157:H7.
Biofilms are composed of aggregated cells and, consequently, they become a suitable environment for the
quorum sensing phenomenon (BASSLER, 2002).
Morphological changes due to
quorum sensing are well characterized in Candida albicans (41,42).
It is important to note that
quorum sensing differs between Gram-positive and Gram-negative organisms, with different signaling molecules, receptors, and associated regulatory pathways in each instance [8,9].
Las caracteristicas adaptativas de los grupos bacterianos, tambien, determinan capacidades de resistencia a antimicrobianos por medio de mecanismos como son la formacion de biopeliculas y de consorcios
quorum sensing, regulando la expresion de genes transmisibles por plasmidos, transposones e integrones.
Quorum sensing en la asociacion beneficiosa de las bacterias con las plantas.
Recently, use of bacterial quorum quenching (disruption of
quorum sensing), has successfully been reported to control the biofilm formation by mineralizing the AHLs in membrane bioreactor systems [5-7].