Reed, "Evidence that sequence-independent binding of highly conserved U2
snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A," Genes & Development, vol.
The researcher says that first is a target-gene binding domain that can be tailored to any gene, while the second domain inhibits mRNA maturation by binding U1
snRNP, a component of the cellular splicing apparatus.
[5] Nonstandard abbreviations: SLE, systemic lupus erythematosus; ANA, antinuclear antibodies; IIT, indirect immunofluorescence test; NALIA, nanodot array luminometric immunoassay;
snRNP, small nuclear ribonucleoprotein; HRP, horseradish peroxidase; PBS, phosphate-buffered saline; CCD, charge-coupled device.
Esto puede ser explicado de dos maneras: analisis in silico muestran que esta mutacion disminuye la afinidad del ARNm con la U1
snRNP (complejo proteico encargado del corte y empalme).
Clinical usefulness of autoantibodies to U I
snRNP proteins in mixed connective tissue disease and systemic lupus erythematosus.
Tudor staphylococcal nuclease (Tudor-SN) participates in small ribonucleoprotein (
snRNP) assembly via interacting with symmetrically dimethylated Sm proteins.
The [m.sup.7]G-cap on pre-mRNA is specifically bound by CBC, which facilitates association of the cap-proximal 5' splice site with U1
snRNP. The CBC remains bound to the cap during RNA processing and has an active role in both splicing and RNA export.
Dreyfuss, "The SMN-SIP1 complex has an essential role in spliceosomal
snRNP biogenesis," Cell, vol.
Opk4_1r has homology to a gene that codes for a small nuclear ribonuclear class of protein (
snRNP) which has a motif known as a RNA binding domain (RBD) or ribonucleoprotein (RNP).
For the amplification of nuclear
snRNP UlA DNA, a primer set was developed with one of the primers in an intron and the other in the adjacent exon sequence.