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The drug is a selective
serotonin 5-HT4 receptor agonist which stimulates 5-HT4 receptors in
nerve plexuses in the gastrointestinal tract and has gastroprokinetic
and gastric evacuant effects by enhancing acetylcholine release. * Cary Pope, Oklahoma State University, to study the differential
toxicity of the organophosphorus pesticides chlorpyrifos and parathion,
as well as the threat agents sarin and soman, and their inhibition of
acetylcholinesterase and the accumulation of acetylcholine in a
cannulated rat brain model
Galantamine (Reminyl)--May increase neuron sensitivity to
acetylcholine, thus enhancing the effect of acetylcholine on the brain
in those patients in early or moderate stages of the disease. |
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