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| ? References in periodicals archive |
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There is no cure for Alzheimer's disease, although drugs
called acetylcholinesterase inhibitors improve symptoms in some people
with mild disease. An acetylcholinesterase inhibitor formed via click chemistry
proved to be the most potent noncovalent inhibitor ever found for this
enzyme. The treatment of AD patients is
dominated by the use of acetylcholinesterase inhibitors such as Aricept
(Eisai), Exelon (Novartis) and Razadyne (Johnson & Johnson) although
the use of the NMDA receptor antagonist Namenda/Ebixa (Forest/Lundbeck)
is gaining acceptance, particularly in the treatment of moderate to
severe AD. |
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