Even though formoterol has a rapid onset of action, similar to that of albuterol
, its slower peak effect and prolonged activity make it a better maintenance drug than an acute reliever or rescue agent.
Pretreatment with inhaled budesonide and albuterol
provided significant protection against the toxin-induced bronchoconstriction.
The Circulaire nebulizer has been shown to deliver high doses of [beta]-agonists in 2 to 4 minutes compared with the 45 minutes for a high-dose albuterol
aerosol using current delivery methods.
vials of albuterol
because of "microbial contamination.
In the beginning of 2008, HFA-propelled albuterol
inhalers accounted for only 5%-10% of albuterol
inhaler sales in the market--even though the FDA in 2005 had finalized the end date for the sale of CFC-propelled albuterol
As production of albuterol
CFC ends, patients will have to switch from familiar generics to more-expensive, branded HFA formulations that are not interchangeable despite having the same active ingredient.
COMBIVENT contains albuterol
and should be used with caution in patients with convulsive disorders, hyperthyroidism, or diabetes mellitus, and in patients who are unusually responsive to sympathomimetic amines.
The FDA accepted comments this summer and fall about its plans to remove the "essential use" exemption for all the CFC-based medications other than albuterol
This news release contains forward-looking statements that involve risks and uncertainties, including statements with respect to the impact of the new, bundled, reimbursement rate for XOPENEX Inhalation Solution; Sepracor's belief that tens of thousands of physicians have prescribed XOPENEX Inhalation Solution for many thousands of Medicare Part B beneficiaries with respiratory disease because they believed, in their clinical judgment, that XOPENEX Inhalation Solution was the most appropriate choice; and Sepracor's ability to work with government officials to try to pursue better alternatives to the proposed bundling of XOPENEX Inhalation Solution and generic albuterol
inhalation solution drugs.
Clinical studies in patients with COPD have shown that the combination of ipratropium bromide and albuterol
sulfate provides patients significantly greater improvement in lung function than either component alone.
This increases the likelihood of heart rate increases in patients using lower doses of albuterol
In March 2005, the Food and Drug Administration (FDA) announced a ban on albuterol
metered-dosage inhalers containing ozone-depleting chlorofluorocarbon (CFC) as a propellant by December 31, 2008.