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AFP |
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For HCC biomarkers, alpha-fetoprotein (AFP, 19-fold),
plasminogen activator inhibitor-1 (PAI-1, 9-fold), cytokeratin 8
(6-fold), cytokeratin 18 (3-fold) and cytokeratin 19 (11-fold), were
dramatically increased in arsenic-induced HCC. , has completed
enrollment for a Phase IIa pilot study in patients with rheumatoid
arthritis with its immunomodulatory drug candidate, MM-093, a
recombinant version of human alpha-fetoprotein (AFP). For NSGCTs, tumor markers may be followed; when tumor
markers such as human chorionic gonadotropin or alpha-fetoprotein remain
elevated, salvage chemotherapy is indicated. |
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