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Functional consequences of elimination of i(to,f) and i(to,s): early afterdepolarizations, atrioventricular block, and ventricular arrhythmias in mice lacking Kv1. An electrocardiogram showed a left anterior hemiblock and a first-degree atrioventricular block. The most frequent adverse effects experienced by Cardizem(R)LA-treated patients were lower-limb edema, dizziness, fatigue, bradycardia, first-degree atrioventricular block, and cough |
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