Children in the observation group were given oxygen-driven budesonide
(Astra Zeneca Pty Ltd.
The primary outcome measure--a composite of death or bronchopulmonary dysplasia at 36 weeks postmenstrual age--occurred in 40% of the budesonide
group and 46% of the placebo group (relative risk, 0.
Four trials found no benefit from ICS; one trial (52 children with viral-induced wheeze) found that nebulized budesonide
(400 mg qid for 2 days, then bid for 7 days) decreased respiratory symptom scores (weighted mean difference= -0.
is the active pharmaceutical ingredient in several products approved by the FDA, including products for the treatment of asthma, allergic rhinitis, ulcerative colitis and Crohn's disease.
To evaluate whether nebulised budesonide
reduces the duration of exacerbation.
As the study progressed, the children who took the budesonide
remained one-half inch shorter through adulthood than the children who did not use the drug, said Strunk, who treats children with asthma at St.
Patients with past history of hypersensitivity to budesonide
, history of treatment of asthma within four weeks prior to study were excluded.
In addition, the mean cumulative exposure to budesonide
was reduced significantly (by 104 mg) over the year-long treatment period in the intermittent vs.
From a clinical practice perspective, it would seem justified to recommend the budesonide
9-mg once-daily regimen, since this would be expected to improve adherence," said Dr.
She received inhaled budesonide
for recurrent cough and bronchodilator-responsive wheeze and was later prescribed intranasal budesonide
for allergic rhinitis.
TORONTO -- Inhaled corticosteroids such as budesonide
and beclomethasone are the best bet for treating moderate, persistent asthma in pregnant women, according to Dr.
SAN FRANCISCO -- Psychiatric symptoms are only half as likely to occur in patients with Crohn's disease treated with oral budesonide
, compared with prednisolone, Dr.