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CABP |
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2+] becomes bound to calsequestrin (CSQ), which is the major calcium binding protein in the sarcoplasmic reticulum (3). EF's catalytic activity requires the binding of calmodulin, a eukaryotic calcium binding protein (54). Previous x-ray diffraction studies of the calcium binding protein, blood coagulation factor XIII, showed that strontium substitution alters the ligating environment of the divalent cation (67). |
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