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cccDNACovalently Closed Circular Deoxyribonucleic Acid
References in periodicals archive ?
Thus, detection of cccDNA and viral RNA in liver tissue of baboon 9732 showed that HBV was replicating.
There is a possibility that more effective drugs or combination therapies, which can reduce intrahepatic cccDNA effectively, will be able to shorten the therapy period in the future.
Attainment of HBeAg or HBsAg seroconversion with therapy is rarely seen, especially in HIV-infected individuals, given the stability of the cccDNA reservoir within infected hepatocytes.