Alpha-lipoic acid attenuates cisplatin
induced acute kidney injury in mice by suppressing renal inflammation.
This finding that curcumin enhances Cisplatin
means that, in the future, we may be able to give this chemotherapy in lower doses.
In another experiment with rats treated with cisplatin
, the addition of 250 mg/kg DHA prevented lethal kidney toxicity in 88% of the animals that received it, while none of the rats that received cisplatin
In an ongoing clinical trial, 786 women with ovarian cancer were randomized to receive paclitaxel plus carboplatin (399 patients) or paclitaxel plus cisplatin
Even for children receiving uniform therapy, there is substantial variability in their hearing damage after cisplatin
treatment, and we suspect this has to do with differences in patients' genetic make-up," said co-corresponding author Jun J.
The Portrazza approval is based on the results of SQUIRE, an open-label, randomized, multi-center Phase III trial that compared first-line treatment with Portrazza in combination with gemcitabine and cisplatin
to treatment with gemcitabine and cisplatin
alone in patients with metastatic squamous NSCLC.
The cells were next treated with 0, 1, or 5 [micro]g/ml Aa-EE with or without cisplatin
Previous research suggested that imatinib is a fertility-protecting drug against cisplatin
, but reports of the drug's effectiveness have been contradictory, Kim said.
We tested this nanovehicle containing cisplatin
on breast and ovarian cancer bearing mice," explained Dr Sudipta Basu, Ramalingaswami Fellow at IISER who led the research.
Editor's note: Furthermore, mice treated with DIM alone or DIM and cisplatin
experienced retarded growth of implanted ovarian tumors compared to untreated mice or animals that received cisplatin
Prior to exposure to aminoglycoside or cisplatin
therapy, all patients underwent baseline pure-tone audiometry in the range of frequencies from 0.
Now, research carried out in Britain has shown that adding cisplatin
to radiotherapy to treat cervical cancer cuts the chance of dying by 23%.