| Acronym | Definition |
|---|
| COT | College of Occupational Therapists (UK) |
| COT | Car of Tomorrow |
| COT | Commitment of Traders |
| COT | Cup of Tea |
| COT | Cotangent |
| COT | Committee on Toxicity (UK) |
| COT | City of Tucson (Arizona) |
| COT | At the Coast (general aviation) |
| COT | Customer-Owned Tooling |
| COT | Central Office Terminal |
| COT | Commonwealth Office of Technology (Kentucky) |
| COT | Commercial Off the Shelf |
| CoT | Caverns of Time (World of Warcraft gaming) |
| COT | Certified Ophthalmic Technician |
| CoT | Completely Off Topic |
| COT | Cyclooctatetraene |
| CoT | Cursor on Target |
| COT | Cost of Transfer (banking) |
| COT | Consecutive Overseas Tour |
| COT | Cancer Osaka Thyroid |
| COT | Coin Operated Telephone |
| COT | Crossroads of Twilight (book) |
| COT | Carnitine Octanoyltransferase |
| COT | Class of Trade (marketing) |
| COT | Center for Ocean Technology |
| COT | Customer-Originated Trace (Nortel) |
| COT | Colombia Time (Colombia time zone) |
| COT | Continuity Testing |
| COT | Chain of Title (ownership claim) |
| COT | Central Office Trunk |
| COT | Cost of Testing |
| COT | Central Office Technician |
| COT | Chief of Transportation (US Army, Ft Eustis, VA) |
| COT | Change of Trend (finance) |
| COT | Class of Traffic (ITU-T) |
| CoT | Cave of Trials (game) |
| COT | Customer Office Terminal |
| COT | Conditions of Tender |
| COT | Cause of Transmission |
| COT | Commissioned Officer Training course |
| COT | Certificate of Transport |
| COT | commanding officer of troops (US DoD) |
| COT | Card or Tape (old term for computer storage media) |
| COT | Channel of Trade |
| COT | Change of Trim (International Association of Drilling Contractors) |
| COT | Continually On-line Trained |
| COT | Commercial Off-The-Shelf Technology |
| COT | Computer Operator Terminal |
| COT | crisis operations team (US DoD) |
| COT | Container Off-Loading and Transfer System |
| COT | Cooperative Occupational Training |
| COT | Consolidated Operability Test |
| COT | Cadet Orientation Tour |
| COT | Critical Operating Task |
| COT | Commercial Off-Topic |
| COT | Counter Obstacle Team |
| COT | Clerical Office Technician |
| COT | Consolidated Operability Trial |
| COT | Contractor's Operations Trial |
| COT | Cargo Only Tank (Oil Tankers) |
| COT | Continuous Time of the Day |
| COT | Component Operability Test |
| COT | Community Outpatient Treatment (healthcare) |
| COT | Current Operating Time |
| COT | Church of Thyatis (fictional, Dungeons & Dragons) |
| COT | Community Outreach Team (various locations) |
| COT | Conventions d'Occupation Temporaire (French: Temporary Occupancy Agreement) |
| COT | Club Omnisports de Tarentaise (French multisport club) |
| COT | Carbone Organique Total (French: Total Organic Carbon) |
| COT | Committee on Technology (various organizations) |
| COT | Chronic Opioid Therapy |
| COT | Community of Trust (various organizations) |
| COT | Certificate of Test |
| COT | College of Textiles (North Carolina State University) |
| COT | Coil-Out Temperature |
| COT | Chicago Opera Theater (Chicago, IL) |
| COT | Clandeboye Oldtimers (est. 1977; Canada) |
| COT | Contrat d'Objectif Territorial (French: Territorial Target Agreement) |
| COT | Council of Trent (Roman Catholic Church) |