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Insulin analogs and premixed insulin analogs, flexible insulin regimens, continuous subcutaneous insulin infusion with an insulin pump, and the recently approved agents that mimic amylin and GLP activity can provide the means for more closely replicating the normal physiologic profile of insulin secretion. Reduction in severe hypoglycaemia with long-term continuous subcutaneous insulin infusion in Type 1 diabetes. Three or four daily insulin injections are given, or the person uses an insulin pump for continuous subcutaneous insulin infusion (CSII). |
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