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CGMP |
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Known as cyclic guanosine monophosphate, or cGMP, the chemical may also play a role in the normal control of any mammal's digestive system. 5) CGRP acts on endothelial receptors and activates a series of intracellular processes that ultimately lead to an increase in cyclic guanosine monophosphate levels and resultant vasorelaxation. Nitric oxide is a biogenic messenger, an EDRF (15,16), and it activates the guanylyl cyclase system (17) [it converts guanosine triphosphate to cyclic guanosine monophosphate (cGMP)], raising the cGMP pool and therefore inducing, among other things, vasodilatation (17) by lowering the intracellular calcium ion (16). |
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