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d4T |
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However, switching away from certain NRTIs--particularly d4T (stavudine or Zerit)--in several studies proved helpful in decreasing the rate of peripheral fat loss, or even in restoring it. The researchers also found that lipoatrophy was significantly associated with d4T use, and called for "improving access to alternative less-offending drugs like tenofovir and abacavir. In January 2001 the Food and Drug Administration (FDA) issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died. |
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