References in periodicals archive ?
However, it is also reported that mTOR inhibitors or PI3K/mTOR dual inhibitors led to resistance by MYC-driven elevation of eIF4F complex (Ilic et al.
Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.
The 43 S complex is recruited to the cap at the 5[prime] end of the mRNA by eIF4F (composed of eIF4E, eIF4G, and eIF4A).
Quando a 4E-BP1 e fosforilada, o eIF4E e liberado e pode unir-se, ao eIF4G e o qual esta tambem sob o controle do MTOR e ao eIF4A, formando o complexo ribossomal eIF4F.
Quando a 4E-BP1 e fosforilada, o eIF4E e liberado e pode unir-se ao eIF4G--o qual esta tambem sob o controle do mTOR--e ao eIF4A, o que forma o complexo eIF4F.