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References in periodicals archive ?
Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo.
In view of the growing evidence that the use of ethambutol is safe in young children, the WHO recommends that similar to adults this drug should be used in all paediatric cases irrespective of the aged.
972 for ethambutol resistance, increasing at a yearly rate of 1.
A prospective, randomized trial examining the efficacy and safety of clarithromycin in combination with ethambutol, rifabutin, or both for the treatment of disseminated Mycobacterium avium complex disease in persons with acquired immunodeficiency syndrome.
Rapid diagnosis of drug resistance to fluoroquinolones, amikacin, capreomycin, kanamycin and ethambutol using genotype MTBDRsl assay: A meta-analysis.
tuberculosis for susceptibility against isoniazid, rifampicin, ethambutol, and streptomycin.
Isolate 1 Isolate 2 Isolate 3 detected detected detected resistance resistance resistance Phenotypic drug Rifampicin; Rifampicin; Rifampicin; susceptibility Isoniazid Isoniazid; Isoniazid testing (DST) (a) Pyrazinamide Ofloxacin; (b) Pyrazinamide Ethambutol (c) Genotype MTBDRplus NA Rifampicin Rifampicin (R; H) Isoniazid Isoniazid Genotype MTBDRsl NA Ethambutol Ethambutol FQ (E; FQ; SLID) WGS NA Available (see Available (see Table 2) Table 2) NA, not available; R, rifampicin; H, isoniazid; E, ethambutol; FQ, fluoroquinolones; SLID, second line injectable drugs.
Visual impairment was observed in only 2 patients in whom the offending drug ethambutol was withdrawn from the treatment regimen.
Interestingly, as illustrated in the case study, it has been reported that up to 6% of those taking ethambutol experience toxic optic neuropathy with signs and symptoms appearing between four and 12 months after initiating treatment.
The trial reported at the 20th International AIDS Conference in Melbourne entailed testing PaMZ against standard drugs - isoniazid, rifampicin, pyrazinamide and ethambutol - among 207 volunteers in South Africa, a fifth of whom were co-infected with HIV.
Antituberculous therapy including rifampin, isoniazid, pyrazinamide, and ethambutol offers a good prognosis for patients, generally curing the disease without any sequelae.
3] = 2 months of initial phase treatment with Rifampicin, Isoniazid, Ethambutol, Pyrazinamide and 4 months continuation phase treatment with Rifampicin and Isoniazid given 3 times per week.