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As compared with histologically normal surrounding lung, lower levels of gelsolin expression has been found in lung cancers. Straube further commented, "We hope this is the first step to demonstrating that using rhu-pGSN replacement therapy to increase plasma gelsolin levels above a critical threshold will prevent critically ill patients from developing many of the life-threatening complications that appear to be strongly associated with hypogelsolinemia, including Gelsolin is a naturally occurring protein found inside cells as well as in the plasma. |
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