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PEEPi |
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In addition, any increase in EELV above relaxation volume results in an intrinsic positive end-expiratory pressure (PEEPi), which must be overcome before inspiratory flow can start (11). Studies of patients in intensive care units have shown that the resistive and elastic work of breathing increases significantly during exacerbations, which leads to a marked increase in intrinsic positive end-expiratory pressure (11, 12). In these patients, delayed cycling can worsen dynamic hyperinflation and intrinsic positive end-expiratory pressure (PEEP^sub i^), increase the number of nontriggering breaths and promote patient-ventilator asynchrony, increase the work of breathing (2, 5), and interfere with breathing pattern (6). Impact of Expiratory Trigger Setting on Delayed Cycling and ... by Didier Tassaux and Marc Gainnier and Anne Battisti and Philippe Jolliet / American Journal of Respiratory and Critical Care M |
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