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References in periodicals archive ?
Specific to methotrexate, SNPs in methylene tetrahydrofolate reductase (MTHFR) are consistently associated with enhanced methotrexate-mediated bone marrow toxicity but only poorly correlated, at best, with response to methotrexate therapy.
7, 2015 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) and Incyte Corporation (NASDAQ: INCY) today announce detailed data from the pivotal phase 3 RA-BEGIN study, which show investigational baricitinib alone and in combination were superior to methotrexate monotherapy in helping patients achieve clinical remission.
So we have a few data suggesting that methotrexate may be modestly effective in treating PsA," Dr.
The necessary equipment for this analysis is highly portable and costs about $10,000--a small fraction of the cost of hardware currently used to track methotrexate.
Methotrexate doesn't resolve the risk of rupture--the main concern with watchful waiting--since ectopic pregnancies can rupture even as the beta-hCG levels decline.
This was due to the increased risk of complications, including emergency surgery, repeated admission and subsequent doses of methotrexate.
Dr Walker, also an honorary senior lecturer at Newcastle University, said: "Nurses throughout the UK play an important role in providing information to patients on drugs such as methotrexate, including its benefits, how to take it, possible side-effects, and what needs to be quickly reported to their medical team.
Methotrexate has also been shown to induce adenosine release in humans.
molecular ions) for methotrexate (MP Biochemicals) and its deuterated internal standard, methotrexate-[d.
This case report presents a patient with MTSS which was not caused by excessive axial loading of the tibia but which was likely due to methotrexate osteopathy.
Various EEG patterns reported in patients with methotrexate overdose may have been due to intrathecal methotrexate overdose or due to systemic high-dose methotrexate given concomitantly (2), (5), (6).
Methotrexate is followed by treatment with a second chemotherapy drug called asparaginase.