In 16 of the 27 monozygotic
twin pairs participating in the study, one member of the pair had been exposed to cytomegalovirus but the other had not.
The genetic differences found and the method used provide a solution to solve forensic and paternity cases involving monozygotic
twins as originator of DNA traces in crime, or as alleged fathers.
Some years ago, one (Twin A) of a pair of apparently monozygotic
twin girls (Twins A and B) approached the genetic counselling clinic for a consultation regarding predictive testing for HD.
Twin studies have shown that monozygotic
twin sisters are frequently, if not always, discordant with respect to preeclampsia and/or HELLP.
Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic
analysis, as twins share the same mtDNA, and monozygotic
twins would share identical nuclear DNA.
The difference in findings between the monozygotic
twin studies and the VHIP is likely due to differences in the severity of cerebral dysfunction.
Twins may be monozygotic
(from single egg) which are identical twins and of same gender.
Twin studies have shown a 60% to 90% concordance rate for classic autism among monozygotic
twins depending on the use of narrow or broad diagnostic criteria.
Genetics Does Not Explain Everything: Discordance in Monozygotic
By referencing the occasional irregularities in embryonic development (such as the development of monozygotic
twins) as well as the ordinary genetics of cell division, Molhoek uncovers the flaws in the reductionistic conflation of genome and identity, and in doing so removes some of the ethical barriers to human cloning.
In utero exposure to diethylstilbestrol (DES), maternal prepregnancy or gestational diabetes, and having been born from a monozygotic
multiple birth were most strongly associated with early-onset fibroids.