The researchers genetically altered a single building block in the nAChR
protein and tested mice for their ability to hear.
In the developing mammalian brain, the vulnerability to chlorpyrifos emerges coincidentally with that of nAChR
expression, so that at the neural tube stage, interference with mitosis and production of apoptosis show a specified progression with nAChR
Previous studies have revealed that the aging process is associated with the remodeling of NMJs and the dispersion of nAChR
agonists for cognitive deficit and negative symptoms in schizophrenia: a meta-analysis of randomized double-blind controlled trials.
Therefore, altered ACh neurotransmission may contribute to the cognitive and behavioral symptoms of schizophrenia because the ACh system is also widespread throughout the cortex and acts at multiple mAChRs and nAChRs
We observed that while MM (an nAChR
antagonist) treatment during gestational period alone did not significantly affect alveolarization and [L.
Schering, Die Schwerkraft im Gaussischen Raume, Nachr
Nos insetos, o nAChR
encontra-se amplamente distribuido e e predominante nas regioes neuropil do sistema nervoso central.
Human laboratory studies have shown that mecamylamine, a nonselective nAChR
antagonist approved for hypertension, can reduce alcohol preference and the stimulating effects of alcohol in healthy study participants (Blomqvist et al.
Yuan-Soon Ho of the Taipei Medical University, and colleagues found that human breast cancer cells consistently over-expressed the alpha 9 subunit of the nAChR
(nicotinic acetylcholine receptor).
To investigate whether the nAChRs
were involved in the synaptic modulation of TDE, pancuronium bromide, a non selective nAChR
antagonist, was used.