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NMS |
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2) It is unclear whether phenothiazines trigger malignant hyperthermia, but they can cause neuroleptic malignant syndrome, which is characterized by hyperthermia but which has a different pathophysiology and treatment. With regard to non-anesthetic-induced reactions, Denborough stated that "the MH myopathy has varied clinical presentations, including heatstroke, gross rhabdomyolysis after a variety of triggers [such as a military march, 200-m sprint training, an influenza-like illness, or a gas from fire extinguishers[8]], a chronically raised serum CK, muscle pain, neuroleptic malignant syndrome (NMS), and sudden infant death (SID). The complication is referred to as neuroleptic malignant syndrome, or NMS. |
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