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Major groups of traditional ototoxic agents in humans Aminoglycosides Cytotoxic agents Amikacin Bleomycin Dihydrostreptomycin Carboplatinum Gentamicin Cisplatinum Kanamycin Nitrogen mustard Neomycin Vincristine Netilmicin Streptomycin Others Tobramycin Acetylsalicylic acid Arsenicals Loop diuretics Quinine Table 2. Other currently available but unapproved treatments for early-stage CTCL, including nitrogen mustard and carmustine, may be limited by allergic hypersensitivity reactions, commercial availability, and an increased risk of secondary skin cancers. Treatments currently available for early-stage CTCL, such as nitrogen mustard and carmustine, are generally applied daily to the patient's whole body; this can be a time-consuming and difficult task for many patients, especially those who live alone. |
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