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References in periodicals archive ?
By using a test tube model, they found that by adding nortriptyline to the alpha-synuclein proteins, they began to move and change shape much faster, preventing the proteins from clumping together.
Mean dosage in clinical trials 45 mg/d (20 to 80 mg/d) (3) Duloxetine Diabetic neuropathy Yes 60 mg/d (dosages >60 mg/d showed no benefit) (4) Fibromyalgia Yes 30 to 60 mg/d (4) Chronic Yes 30 to 60 mg/d (4) musculoskeletal pain Imipramine Neuropathic pain No 50 to 150 mg/d (5) Amitriptyline Diabetic neuropathy No 25 to 100 mg/d (5) Chronic pain No 25 to 150 mg/d (6) management Migraine prophylaxis No 10 to 150 mg/d (7) Nortriptyline Chronic pain No 10 to 150 mg/d (8) Myofascial pain No 12.
4) Like nortriptyline, however, clonidine is not FDA-approved for this purpose and is not considered a first-line agent.
Drawbacks: Abruptly stopping nortriptyline after prolonged use may cause nausea, lethargy and a general feeling of illness.
Gabapentin and nortriptyline combined was better than either drug alone for relief of neuropathic pain.
These new neuropathic symptoms were reduced by nortriptyline, but not completely controlled, and the patient found the symptoms to be very hard to tolerate.
Sixty-eight type 2 diabetic patients with poor glycemic control, 28 of whom had active major depression (DSM-IIIR), completed a randomized, double-blind trial of eight weeks of treatment with nortriptyline in doses to achieve blood levels of 50-150 ng/ml.
1-3) Either amitriptyline or nortriptyline were started at 10 mg once daily in the evening.
Sexual dysfunction in women suffering from postpartum depression (PPD) improves once the depression is remitted regardless of what antidepressant is used, according to a clinical trial comparing nortriptyline versus sertraline for PPD in 70 women.
A Tricyclic antidepressants (TCAs), such as amitriptyline (Amitril, Elavil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil) and nortriptyline (Pamelor, Aventyl), are commonly used to treat chronic pain.
Teesside Coroner's Court heard how tests had shown that Mr Pearson's body contained high levels of the anti-depressant Nortriptyline, and the painkiller Tramadol.
There were four RCTs of nortriptyline (Aventyl/Pamelor) without NRT, totaling 777 smokers followed for at least 6 months.