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p53

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
AcronymDefinition
p53Tumor Suppressor Gene


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They have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 - a gene mutated in the majority of human cancers.
Previous studies have demonstrated that p53 stops cancer from developing by sensing stress, such as DNA damage, and turning on genes that prevent cells from dividing.
Cytoplasmic p53 accumulation is related to increased hepatocarcinoma malignancy.
 
 
 
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