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Differential responses of rat alveolar and peritoneal macrophages to man-made vitreous fibers in vitro. Peritoneal macrophages were isolated by flushing the peritoneal cavity of A/J mice with 10 mL of sterile ice-cold phosphate buffer. To investigate the toxic effects of environmental DU exposure on the immune system, we examined the influences of DU (in the form of uranyl nitrate) on viability and immune function as well as cytokine gene expression in murine peritoneal macrophages and splenic CD[4. |
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