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PHT |
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CoTherix plans to introduce the agent for the treatments of angina (an oral formulation) and pulmonary hypertension (both oral and inhaled formulations). Human herpesvirus 8 (HHV-8) antibodies were detected in 1 of 33 patients with pulmonary hypertension (including in 1 of 16 with idiopathic pulmonary arterial hypertension), 5 of 29 with cystic fibrosis, and 3 of 13 with interstitial lung disease. FDA'S decision to approve sildenafil for pulmonary hypertension took into account several studies, including one with 277 patients who had, as adults, developed pulmonary hypertension for various reasons. |
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