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Chronic hyperphosphatemia is associated with serious health risks including renal osteodystrophy (resulting in bone pain, brittle bones, skeletal deformities and fractures), and heart failure caused by cardiovascular calcification. Chronic renal failure and renal dialysis have been associated with renal osteodystrophy. Other kidney-disease-related disorders, including renal osteodystrophy (a collective name for several forms of metabolic bone disease) and vascular calcification (a form of cardiovascular disease that involves mineralization of the blood vessels), have proven much more difficult to treat successfully. |
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