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All cefoxitine-resistant isolates underwent further identification and susceptibility testing to cefoxitine, gentamicin, vancomycin, teicoplanin, clindamycin, erythromycin, rifampicin, ciprofloxacin, cotrimoxazol, and tetracycline, using the Phoenix Automated Microbiology System (Becton Dickinson, Franklin Lakes, NJ, USA). Leprosy is now typically cured with multiple drug therapy (some combination of rifampicin, clofazimine and dapsone) administered for six to 12 months, sometimes longer. Rifampicin (RIF) and pregnenolone 16[alpha]-carbonitrile (PCN) were purchased from BioMol (Plymouth Meeting, PA). |
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