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Polymorphism in PfATPase6 and G7 genes and in vitro susceptibility to dihydroartemisinin of 154 Plasmodium falciparum isolates * Gene Predicted products Position Amino acid ATPase6 Sarcoplasmic reticulum 769 S calcium-transporting ATPases S [right arrow] N 263 L L [right arrow] S 243 H H [right arrow] Y G7 ABC transporter 1,390 Wild Mutant (3-bp indel) Nucleotide No. 2+] release from sarcoplasmic reticulum isolated from rabbit muscle cells, but 3,3',4,4',5-CB does not alter [Ca. To make the muscle contract and relax, calcium goes from the sarcoplasmic reticulum to the myoplasm and back. |
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