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Five years ago, however, the Galveston researchers uncovered evidence that the bulk of the pain from the internal organs, or viscera, travels up the overlooked dorsal column, while the spinothalamic tract carries pain messages predominantly from the skin and muscles. [17] In anesthetized animals with intact spinal cords, electrical stimulation has been shown to produce a sustained inhibitory effect on the flexion reflex and neuronal activities of spinothalamic tract cells lasting up to 20 minutes,[18-20] which can be reversed by naloxone. |
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