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Related to stavudine: zidovudine, nevirapine, delavirdine, didanosine
d4TStavudine (aka Zerit; HIV treatment drug)
d4TDidehydrodeoxythymidine (antiviral drug)
References in periodicals archive ?
Highly active antiretroviral therapy regimens (N=64) Patients, n Stavudine (NRTI)/lamivudine (NRTI)/efavirenz (NNRTI) 56 Stavudine (NRTI)/lamivudine (NRTI)/nevirapine (NNRTI) 4 Zidovudine (NRTI)/lamivudine (NRTI)/efavirenz (NNRTI) 1 Stavudine (NRTI)/nevirapine (NNRTI)/didanosine (NRTI) 1 Lamivudine (NRTI)/efavirenz (NNRTI)/tenofovir (PI) 1 Lamivudine (NRTI)/didanosine (NRTI)/nevirapine (NNRTI) 1 NRTI = nucleoside reverse transcriptase inhibitor; NNRTI = non-nucleoside reverse transcriptase inhibitor; PI = protease inhibitor.
The reasons for lower prevalence in our study could be due to shorter follow up and less number of patients on stavudine regime.
Patients on ARV treatment who experienced SHL/LA were classified as cases, and those patients on treatment with stavudine for [greater than or equal to] 24 months as part of their HAART regimen who did not experience SHL/LA were classed as controls.
Zidovudine was implicated in the highest number of ADRs, followed by nevirapine and stavudine.
There are caveats: Early ART is not a reasonable option in facilities still using stavudine or zidovudine as first-line treatment, nor in facilities prone to stock-outs.
In the duration of 1 year on ART two changes in regimen and six changes in the strength of the drug stavudine had occurred.
Of all patients receiving the combination stavudine, lamuvidine and efavirenz (n = 68), 72% were depressed.
Substitution T215Y causes intermediate resistance to zidovudine and stavudine and low-level resistance to abacavir, didanosine, and tenofovir.
Zidovudine was prescribed if the haemoglobin was more than 8 g/dl and stavudine based regimen was started if the haemoglobin was <8 g/dl.
Its experts also want to see the phasing out of the drug Stavudine, which is widely used in developing countries due to its low cost and widespread availability.
The WHO also said on Monday that countries should phase out the use of stavudine, the most common AIDS drug, because of "long-term, irreversible" side effects in HIV patients including wasting and a nerve disorder.
HIV suppression with stavudine 30 mg versus 40 mg in adults over 60 kg on antiretroviral therapy in South Africa.