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On a monthly basis, medication use and cost was measured and reported the number of medications and medication doses per nursing home resident per month; the number of laboratory measurements for narrow therapeutic index drugs per nursing home resident per month; and the cost of all oral medications per nursing home resident per month. Finally, development of newer drugs offering similar activity against both enzyme targets (DNA gyrase and topoisomerase-IV), as well as an improved therapeutic index, will definitely strengthen clinical practice. Chemotherapy drugs have traditionally had a therapeutic index of no better than 6 to 1, meaning that they destroy up to 6 cancer cells for every healthy cell that dies. |
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