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Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. To test whether the relative amounts of essential fatty acids in the diet affects colitis-related damage, Natalia Nieto and her colleagues at the University of Granada in Spain induced ulcerative colitis in a group of rats by administering a substance known as trinitrobenzene sulfonic acid through a tube into the animals' colons. Quantitation of [epsilon]-amino groups using amino acids as reference standards by trinitrobenzene sulfonic acid. |
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