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Visceral leishmaniasis or kala-azar, the often fatal form of the disease, is caused by species of the Leishmania donovani complex. DNDi's initial drug development efforts are aimed at chloroquine-resistant malaria, human African trypanosomiasis (sleeping sickness), visceral leishmaniasis (also called kala-azar), and Chagas disease. Visceral leishmaniasis is usually curable if caught early, but treatment involves a month or two of daily injections, an expensive regimen for people in developing countries and one that sometimes causes significant side effects. |
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